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Facilities

Biosoft joint lab is an experimental and pre-industrial open facility for implementing soft lithography and optical detection for IVD applications. The platform owns all the materials and infrastructure for implementing soft lithography processes, capillary assembly, biochip fabrication, microfluidic integration and optical biodetection.

  • inno910.png

    InnoScan 1100 : high-resolution 3-color fluorescence scanner

    With a resolution of up to 0.5µm/pixel, this scanner can scan a whole slide into high quality image

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  • InnoStamp 40 : a fully automated microcontact printerInnostamp

    InnoStamp 40 is a user-friendly system for nano and micropatterning.

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  • AutoInk : a microfluidic approach to ink a stamp
    AutoInk

     
    AutoInk is an equipment that permits to ink a stamp with microfluidics. The system consists in a peristaltic pump connected to a mobile pipetting system connected to the inlet and the outlet of the microfluidic device through disposal pipetting cones. It provides both controls of the injection and aspiration of the solutions in the device.
  • Capillary Assembly : a robust capillary assembly equipement
    capa
    This equipment permits to organize biomolecules (DNA, Actin, ...) on stamp by capillary assembly.

  • InnoScan1100 IS1100
  • InnoStamp40 InnoStamp40
  • AutoInk AutoInk
  • Capillary Assembly Capillary assembly

More specifically, the following specific systems are available in our facility:

  • The latest version of the automatic system for multiplexed micro and nano contact printing: Innostamp 40 from Innopsys. (Technical datasheet)
  • InnoScan 1100 AL, the highest spatial resolution fluorescence scanner currently available with 3 excitation lasers (488, 532 and 635nm), latest product of Innopsys family of scanners. (Technical datasheet)
  • The latest version of the diffractive scanner: Diffrascan, enabling the label free optical detection of multiplexed interacting molecular gratings.

 

Close to BIOSOFT room are the academic open facilities of LAAS-CNRS:

  • ALIVE : characterization for chemistry and biologyclean room1

    This area includes the characterization means related to chemistry and biology to microelectronics.

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  • ALIVE : characterization for chemistry and biologyAlive

    This area includes the characterization means related to chemistry and biology to microelectronics.

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  • clean room clean room
  • ALIVE facilities ALIVE

  • The clean room facility (more details) of 1500 m2 (class 100), state of the art platform in nanofabrication, can be employed for the design, fabrication and characterization of the master moulds required for implementing soft-lithography processes.
  • The ALIVE platform of 400 m2 (more details) gives access to various lab techniques of molecular and cell biology and to various associated imaging methods. Level 1 and Level 2 zones are now available for the culture of primary and immortal cells, bacteria, yeasts and algae.
    • Conventional techniques of optical microscopy mainly relying on fluorescence have been gathered inside a dedicated zone where microfluidic networks can be imaged and recorded in video modes and cell immunostaining can be performed.
    • Several fluidic set-ups are also available.
    • A dedicated atomic force microscope from JPK (nanoWizard 3) is also widely used in liquid media for molecular coating and pattern characterizations but also for living cell characterization and force spectroscopy.
    • Electrochemical techniques are also available with various potensiostat/galavanostats and impedance spectrometers.
    • Moreover, as many nanomaterials are embedded in many of our biodevices, several instruments for characterizing (Zetasizer) and manipulating nano-objects, DNA, lipids and other assembling molecules are also available.