Versatile bio patterned substrate

Soft lithography processes can be implemented at low cost and high throughput for industrial applications on a very wide range of inks and receiving substrates. Biosoft lab owns a home-made list of available inks and substrates compatible with automatic micro and nano-patterning. This list includes the patterning of carbon nanotubes, nanoparticles (metallic, semi-conducting, polymeric...), molecular imprint polymers, room temperature spin transition molecular inks, dendrimers, DNA, RNA, peptides, proteins, lipid bilayers, enzymes, oligo and poly saccharides, bacteria, yeast, blood, sweat, urine...

Soft-lithography can address those entities in well-controlled patterns of totally arbitrary shapes and surpasses the current capabilities of conventional ink jet methods. Depending on the ink used the spatial resolution can reach 50 nm and combined with capillary assembly inking techniques single molecule patterning can be achieved. Combined with our home library of surface chemistry, the functionality and conformation of the printed molecules can be optimized. Silicon, glass, plastics, paper, textiles, well-plates can be processed by soft-lithography.

This versatility opens many avenues for application of this method for sensor fabrication, biochips and IVD devices, patterned cell culture substrates, patterned SERS substrates, smart and wearable electronics, cosmetics, identification tags....

Printing on flexible substrate

Microcontact printing could be used to fabricate molecular patterns on flexible substrate. For example, in this video, a fluorescent dye (FITC) is printed on PDMS with a high resolution. The size of the pixel is 1µm.